Daily Aspirin May Not Reduce CV Risk Over Long-Term In Patients Who Have Not Had A Heart Attack Or Stroke, Study Suggests.
The AP (8/26, Marchione) reports that while “taking a low-dose aspirin every day has long been known to cut the chances of another heart attack, stroke or other heart problem in people who already have had one, ” research indicates “the risks don’t outweigh the benefits for most other” people. The findings (8/26) were presented at the European Society of Cardiology meeting and published in the Lancet.
Medscape (8/26, Stiles, Subscription Publication) reports, “Aspirin at a daily dose of 100 mg was not seen to reduce the long-term risk for cardiovascular (CV) or cerebrovascular events in a trial that randomly assigned more than 12, 000 nondiabetic adults with multiple CV risk factors but no history of CV events.” The stroke risk was also not reduced. Medscape adds, “In the study’s primary intention-to-treat (ITT) analysis, 4.29% of persons assigned to aspirin and 4.48% of those in the placebo group experienced the primary endpoint of CV death, myocardial infarction (MI), unstable angina, stroke, or transient ischemic attack (TIA) over a mean of 5 years.